NBA 2K17 is a basketball simulation game which, like the previous games in the series, strives to realistically depict the experience of the National Basketball Association (NBA), as well as present improvements over the previous installments. The player mainly plays NBA basketball games with real-life or customized players and teams. As such, games follow the rules and objectives of NBA basketball games. Several game modes are available for the player and many settings can be customized. The game contains many presentation qualities that are modelled on real-life presentation, such as crowd animations, commentary, pre-game, halftime, and post-game shows, camera angles, lighting, and player animations. The menus have also been modified.
Along with playing games with current NBA teams, such as the Philadelphia 76ers and Toronto Raptors, other teams are featured, such as the 2016 United States men's Olympic basketball team, the Australia men's national basketball team, and the 1992 United States men's Olympic basketball team. 21 EuroLeague teams are also present.
One of the touted improvements is concerning the game's returning MyGM and MyLeague game modes. Both modes have the player acting as the ruling force of all basketball operations for a specific team and allow the player to customize many aspects of the team. MyGM is more focused on maintaining a realistic, functioning team and impressing the owner, whereas MyLeague offers far more customization options. In both modes, the player simulates through seasons, changing personnel, playing in games themselves, and participating in off-season activities, such as the draft. The introduced features focus on league expansion. As well as happening dynamically, the player can start either mode with up to 36 teams and may modify many aspects of every team. The player will go through the process of creating an expansion team in a model very similar to real-life occurrences of expansion teams. As well as creating the logos and jerseys of the teams, an expansion draft is held and other teams must protect a select amount of players. The league will automatically adjust the schedule, draft, draft lottery, etc. if expansion teams are created. The player can also download other players' creations.
MyCareer mode returns. Like previous iterations of the mode in the series, the player creates a basketball player and plays through their career. The player customizes their player's appearance and upgrades their attributes as they play through a college career and enter the NBA. The player plays basketball games and participates in off-court activities. A storyline is also present.