Albert Wesker Vs. Neo

Name: Albert Wesker
Game: Resident Evil
Weapon: Handgun
Occupation: Researcher, Captain (former)
Abilities: Wesker demonstrated hyper-accelerated speed and reflexes, enhanced agility, intensified endurance, increased strength, limited healing factor. These attributes gave him a number of advanced combat capabilities, which he used to craft his own unique martial arts fighting style which perfectly complimented his abilities and personality. The virus he injected also had the added ability of superhuman endurance and near-invulnerability; hardening his skeleton, internal organs, tissue, and skin, to the point that attempting to punch him or engage in hand-to hand combat would most likely result in fractured limbs on the part of the attacker. The hardened skin is also such that it is quite capable of bending metal when struck against. His durability was such that he was able to not only survive being caught in the epicenter of an explosion, but apparently not have any ill effects afterwards.

Notable achievements of his superhuman speed, accelerated vision, and agility included being capable of dodging bullets at practically point blank range with nearly no effort (including rapid fire, multiple shot weapons, grenades, and Rocket Launchers), being able to cover great distances in short time (relatively equal to the time it would take using a fast vehicle), adhering to walls and ceilings like a spider, and performing short dashes of speed faster than the normal Human brain could process.

His aim, while using his weapon, is also quite inhuman as shown at the end of Umbrella Chronicles where he shot a crane hook off from far away with just a handgun. He also had a high tolerance to pain, at least short of being overdosed by the serum.

Notable achievements of his increased strength included being able to lift large missiles with one hand and throwing them, lifting large steel girders off his body, lifting an adult human off the ground with one hand effortlessly, thrusting straight through the chest of a person with his fingertips, killing a chimera B.O.W. with just one kick, sending someone flying with a single backhand swipe, punching an adult human with enough force to shatter a stone door behind them, punching a metal wall inside an airplane hard enough to leave a noticeable dent afterwards and even punching through the same wall later on, and punching through a solid sheet steel missile.

The injection also gave Wesker a low-level rapid healing factor which, coupled with his incredible endurance, rendered him nearly invincible to conventional damage. A rocket exploding right in his hands was only sufficient to stun him for a moment, and thousands of pounds of steel falling a few stories on top of him failed to even incapacitate him, merely dazing him for a few brief seconds, and despite having his face hideously burned, he quickly healed up. He also healed quickly after getting shot in the head by Sheva and falling a great distance out of a jet, and despite being overdosed by his serum.

With these powers, Wesker mainly did not require weaponry other than his brute strength during combat, combined with a sufficient strategy and some meticulous observation. However, he did keep his handgun holstered at all times, and was known to never let his guard down, even outside the battlefield. In rare times, he has also actually used his handgun during battle.

Name: Neo
Movie Series: Matrix
Occupation: Hacker
The One, an anagram for Neo(warrior)
Former software engineer (in the Matrix simulation)
Abilities: Neo has carried, since his inception, The Matrix's source code known as The Prime Program. This gives him the ability to freely manipulate the simulated reality of The Matrix, similar to the authority a system administrator has over a given system. He manifests these abilities as various superhuman powers.

The power Neo exhibits most often is telekinesis, in that he seems capable of manipulating any object in The Matrix through will alone. By focusing this ability upon himself he can fly at amazing speeds and jump great distances. Whilst his speed is never specified, he flies from The Merovingian's mountain manor to the highway "500 miles due south" in a very short time.

His high-speed flight is further exemplified by his ability to escape explosions, and the sonic boom left in his wake has the power to overturn and tow rows of heavy vehicles and debris. His sonic boom almost destroyed a city block while catching Trinity. He has used this ability multiple times to stop several bullets in mid flight, first against the Agents and again against The Merovingian's henchmen.

Further, Neo possesses superhuman strength and agility, and is invulnerable to many attacks. His reflexes are great enough to dodge bullets. Although he could block a sword with the edge of his hand, he received a small cut, indicating (as The Merovingian pointed out) that he was still human, despite his powers. His endurance is also finite: when confronted by masses of Smith clones, Neo was forced to escape rather than continue fighting, and upon exiting The Matrix, he appeared visibly tired. He can also pass through walls. This ability was first shown in The Matrix, when he entered into Agent Smith's body and deleted him and a Sentinel passed through his body in the Machine City in The Matrix Revolutions.

Neo was able to revive the recently deceased Trinity by gently applying pressure on the heart, and thus making it operational once again. Though the extent and limits of his ability to revive within The Matrix are not known.

A more subtle application of Neo's ability is a heightened awareness of the simulated nature of The Matrix, enabling him to easily detect Agents, Exiles, and other anomalous phenomena (such as the presence of explosives). He is even capable of a limited form of precognition.

In addition, Neo (like most "Redpills") utilizes the Resistance's combat programs, which grant combat abilities equivalent to a martial artist with decades of experience. Neo is able to run an unprecedented number of these programs simultaneously; he is therefore a master of every known martial art and fighting styles, including Kung Fu and Kempo styles, Jujitsu, Karate, Eskrima, Drunken Boxing, and Taekwondo. In training for the series, Keanu Reeves' fighting arsenal, as well as the entire cast's, emphasizes Wushu.

I may have gotten some of Neos abilities since it was years ago I saw the movies, so just tell me if something is wrong.